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Tohru Noji Selected Research

3- (1- (6,7- diethoxy- 2- morpholinoquinazolin- 4- yl)piperidin- 4- yl)- 1,6- dimethyl- 2,4- (1H,3H)- quinazolinedione

8/2003[Pharmacological study on the effects of the adenosine uptake inhibitor KF24345 on inflammatory diseases].
11/2002Adenosine uptake inhibition ameliorates cerulein-induced acute pancreatitis in mice.
11/2002KF24345, an adenosine uptake inhibitor, ameliorates the severity and mortality of lethal acute pancreatitis via endogenous adenosine in mice.
8/2002Treatment with an adenosine uptake inhibitor attenuates glomerulonephritis in mice.
1/2002KF24345, an adenosine uptake inhibitor, suppresses lipopolysaccharide-induced tumor necrosis factor-alpha production and leukopenia via endogenous adenosine in mice.

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Tohru Noji Research Topics

Disease

4Inflammation (Inflammations)
07/2004 - 11/2002
3Ischemia
07/2004 - 11/2002
3Pancreatitis
08/2003 - 11/2002
2Glomerulonephritis
08/2003 - 08/2002
2Leukopenia
08/2003 - 01/2002
2Proteinuria
08/2003 - 08/2002
1Pain (Aches)
07/2004
1Brain Injuries (Brain Injury)
07/2004
1Seizures (Absence Seizure)
07/2004
1Thrombosis (Thrombus)
07/2004
1Wounds and Injuries (Trauma)
07/2004
1Sleep Initiation and Maintenance Disorders (Insomnia)
07/2004
1Hyperamylasemia
11/2002
1Necrosis
11/2002
1Edema (Dropsy)
11/2002

Drug/Important Bio-Agent (IBA)

6Adenosine (Adenocard)FDA LinkGeneric
07/2004 - 01/2002
53- (1- (6,7- diethoxy- 2- morpholinoquinazolin- 4- yl)piperidin- 4- yl)- 1,6- dimethyl- 2,4- (1H,3H)- quinazolinedioneIBA
08/2003 - 01/2002
3Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
08/2003 - 01/2002
3QuinazolinonesIBA
11/2002 - 08/2002
2Purinergic P1 Receptor AntagonistsIBA
08/2003 - 11/2002
2CeruletideIBA
08/2003 - 11/2002
2Choline (Choline Chloride)IBA
08/2003 - 11/2002
2Cyclophosphamide (Cytoxan)FDA LinkGeneric
08/2003 - 08/2002
2EthionineIBA
08/2003 - 11/2002
2LipopolysaccharidesIBA
08/2003 - 01/2002
2Prednisolone (Predate)FDA LinkGeneric
08/2003 - 08/2002
1Adenosine Triphosphate (ATP)IBA
07/2004
1Lipase (Acid Lipase)FDA Link
11/2002
1AmylasesFDA Link
11/2002
18-(4-sulfophenyl)theophyllineIBA
11/2002

Therapy/Procedure

2Intravenous Injections
11/2002 - 08/2002
1Organ Transplantation
07/2004
1Intraperitoneal Injections
11/2002